Troxerutin protects against DHT-induced polycystic ovary syndrome in rats
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چکیده
منابع مشابه
Troxerutin Chronic Treatment Protects against Fructose-induced Metabolic Syndrome in Male Rats
Background and Aims: Metabolic syndrome, a common metabolic disorder, for the serious health consequences such as insulin resistance and lipid abnormalities has been considered as a major clinical challenge with obscure causes. Oxidative stress is an important component of metabolic syndrome, contributing in its development. Troxerutin, a semi-synthetic derivative of natural bioflavonoid rutin,...
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Objective : Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders that can lead to irregular menstrual cycles and hyperandrogenism. Reduced levels of progesterone and increased estrogen in these women can perpetually stimulate the endometrial tissue of the uterus. In this study, the effect of PCOS induction was studied using estradiol valerate. MaterialsAndMethods Adult ...
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Two-hundred and seventeen subjects underwent transvaginal ultrasound -17 (8%) had unilateral polycystic ovary (PCO). Twelve percent of subjects with unilateral scan-pea had oligomenorrhea, 24% were amenorrheic, 23% were hirsute and 29% had acne. Biochemical parameters were compared between subjects with unilateral scan- PCO and those with bilateral scan- PCO (n=200) as well as a group of s...
متن کاملMajor Epigenetic Changes in Polycystic Ovary Syndrome
Introduction: Polycystic Ovary Syndrome (PCOS) is one of the most common causes of female infertility. The etiology of this condition is complex. Various genetic and environmental factors have been identified in the pathogenesis of PCOS. The prevalence of this syndrome among Iranian females has been reported between 7.1% to 14.6%. Common symptoms include irregular menstruation, infertility, ova...
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ژورنال
عنوان ژورنال: Journal of Ovarian Research
سال: 2020
ISSN: 1757-2215
DOI: 10.1186/s13048-020-00701-z